Tip 1 

Unless you have unchecked "Show Tips" in Settings, you will be presented with the first tip. After reading it, touch "OK" to continue. If you have "Voice" checked in Settings, the neural monitor will advise you to begin.

Start and end 

The basic idea is to navigate the maze of neurons between the start and end of each level. As you progress, the stages become more challenging and the number of levels in each stage increases.